David Wong's Internet-serialized cult novel gets turned into a trippy sci-fi flick by writer-director Don Coscarelli (Phantasm, Bubba Ho-Tep). A hot new designer drug called "soy sauce" sends its users on a trip across time and space. The biggest side-effect is some of them are no longer human when they return. Now it's up to two college dropouts to save the entire universe from destruction. Part Naked Lunch, part Ghostbusters, part Dawn of the Dead, John Dies at the End is one hilariously gory freakout.99 minutes R.