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 V.19 No.44 | November 4 - 10, 2010 

Miss Diagnosis

Insulin Shock

“Left Over Bits”
“Left Over Bits”

Some diseases, like people, just have a special “it” factor that captures the imagination of the public. For instance, Ebola erupted on the scene with unprecedented dramatic flair. The virus achieved fame by learning to demolish the inner layer of human blood vessels. This little trick causes hemorrhagic death grisly enough to put all those horror-movie faux grotesqueries to shame. Or consider the case of last year’s media darling, the dreaded H1N1 “swine” flu. Like a sadistic serial killer with major mommy issues, this disease made a name for itself by killing off children and pregnant women faster than you could say “front page news.”

But what if I told you about a disease with enough destructive force to make those look like B-movie amateurs? A disease that rivals Ebola in the yuck department, with bleeding retinas, festering foot ulcers and brain clots? More persistent than swine flu, it attacks women and children—and everyone else. This disease upstages other epidemic evildoers by blinding its victims, maiming their kidneys and scrambling their nervous systems. Many people with this disease die only after a prolonged torture of amputation and dialysis.

Diabetes is like the global warming of diseases.

Unfortunately, what’s described above isn’t some reclusive virus that crops up briefly, goes on a rampage and then slinks back into obscurity before wearing out its welcome in the headlines. It’s not some pandemic that can be controlled with vaccination and hand-washing. In fact, it’s not an infection at all. It’s that familiar, stealthy old juggernaut known as type 2 diabetes mellitus. And with a bag of Halloween candy still lying around, the Thanksgiving feast being planned and Christmas cocktail parties just around the corner, ’tis the season for elevated blood sugar.

Diabetes is like the global warming of diseases. Its mechanism of planetary destruction is elegantly simple. When you eat, your body breaks down food into sugar molecules that are absorbed into your bloodstream. Sugar in the blood is then sucked up by all the little cells in your body that use it for energy.

Essentially, the extra sugar tears through the body’s most delicate parts like tiny shards of glass.

However, sugar molecules need a doorman to let them into the cell. Insulin, a hormone produced by the pancreas in response to rising blood sugar, unlocks the little doors on the outside of the cell, allowing sugar to enter. Without insulin, sugar is left out in the cold, knocking hopelessly on a locked door.

If sugar can’t get inside the cell, it just loiters around in the blood stream. Unfortunately, sugar is a clunky molecule, and it likes to stick to the inside of your blood vessels. This damages them the way that rust can damage a shiny piece of metal. Essentially, the extra sugar tears through the body’s most delicate parts like tiny shards of glass.

Excess weight, poor diet, a sedentary lifestyle and genetics can cause metabolic changes in the body that alter the way cells respond to insulin. In type 2 diabetes, the cells gradually become unresponsive. The pancreas reacts by dumping even more insulin into the blood stream, trying to overwhelm the unresponsive cells. But eventually the insulin-producing cells in the pancreas become exhausted and burn out.

This is not just about people drinking too many sodas and watching too much television.

These changes happen gradually, and damage from rising blood sugar accumulates almost imperceptibly. This is why diabetes lacks the shock value of Ebola. If you tell someone, Hey, in one week you’re going to start hemorrhaging massively out of your face and ass, the motivation to change is pretty strong. But telling someone that they are going to lose a leg and kidney in 25 years doesn’t quite pack the same punch.

Most cases of type 2 diabetes are directly related to weight and lifestyle, although there is a strong genetic component. Not everyone who has the disease is overweight or sedentary. The last guy I took care of with type 2 diabetes was probably 125 pounds dripping wet. Certain minority groups are more likely to get the disease, even when matched for weight and age to their Caucasian counterparts. Minorities also tend to develop a more aggressive form of the disease. Add this to the fact that minorities are less likely to have access to insurance and health care, and you’ve got a recipe for disaster.

Despite the genetic component, type 2 diabetes is almost completely preventable. Diabetes is the seventh leading cause of death in this nation, and it affects nearly 8 percent of the general population. Can you imagine if 8 percent of the population was hooked up to life support and dying of respiratory failure like H1N1 victims? What do you think people would do?

In 2007, diabetes cost our country $174 billion dollars. The Centers for Disease Control and Prevention projects that rates of diabetes will double or triple by 2050, and that as many as one in three Americans will be afflicted by the disease. What would we do if one in three Americans started bleeding out of their eyeballs and vomiting up blood like Ebola victims?

Clearly, diabetes is a public health issue that raises more questions than answers. This is not just about people drinking too many sodas and watching too much television. This disease is steeped in cultural and economic factors like poverty, education, family structure, employment opportunities and access to care. It’s easy to tell people to diet and exercise. It’s hard to create an environment in which people actually have the knowledge, motivation, and social and financial resources to make it happen.

Diabetes won't abdicate its destructive throne on its own. We, as a society, must empower one another to make the necessary changes. So our first challenge, as we move into a future in which one in three Americans could develop diabetes, is to make this real to people. If this means I have to rant and rave about gross amputations, pustulant ulcers and ugly death in my column, so be it.

Despite its brilliant name, this column is not intended to prevent, diagnose or treat herpes. Or any other diseases, for that matter.

Whitny Doyle is a family nurse practitioner grad student.

The opinions expressed are solely those of the author.
Public Comments (7)
  • Another gruesome fact about DM...  [ Wed Nov 3 2010 9:16 PM ]

    Not to be outdone, I think one other method to wake the masses is to tell about the little known fact of impotence among men with uncontrolled Diabetes...

    But I agree, takes more than just telling people to exercise and diet. Much of our society does not value health promotion. Wouldn't it be nice if P.E. were back in schools? The increase in Diabetes in children is devastating. Wouldn't it be nice if people had to take an additional break to do Tai Chi or walk off their daily stress? How much money we could save and how much happier a society we could be with such little things...

  • What a refreshing take on the subject! NOT.  [ Fri Nov 5 2010 5:46 PM ]

    This is a boring rehash of every other diabetes article everywhere in the media, and it ought to be obvious from the statistics that this type of scare-tactic, victim-blaming/shaming reporting IS NOT HELPING.

    Despite the genetic component, type 2 diabetes is almost completely preventable.

    O RLY? How many other diseases with a "genetic component" are considered "almost completely preventable" (and so what's wrong with you for not preventing yourself from getting sick)? If it actually were the case, one would think that diabetes would be prevented by now, given that these talking points can be found anywhere and everywhere the topic arises. Contrast Miss Diagnosis' "facts" with this recent statement from Diabetes Daily:

    Lastly, let's clear up a major myth. When someone gets type 2 diabetes, it is not their fault. Type 2 diabetes has a strong genetic link (even more so than type 1). If your twin has type 2 diabetes, you have almost a 100% chance of developing it. While staying fit can substantially delay the onset of type 2 diabetes, it does not guarantee prevention. If you have the "right" genes and live long enough, you will most likely develop diabetes. And if you don't have the genes? You can gain weight and barely increase your risk at all.

    If you were someone with diabetes -- which the people that write these useless articles almost never are, oddly enough -- which set of ideas would help you more -- "You're going to die horribly and it's all your fault, plus you're costing us a buncha money you lazy fat pigs!" versus "It's not your fault, let's talk about what you need to take the best care of yourself that you can." As a person with diabetes, I know which one I pick, and I'm sick and tired of being blamed for my difficulties and addressed as though I'm too stupid to know what's good for me by authors of articles like this one.

    I would think that, given the health care crisis that's all over the news, Miss Diagnosis and that radical publication The Alibi would be loathe to spew the same old same old garbage you can read anywhere. The fact that you think this crap is worth publishing explains perfectly why I keep my diagnosis a secret.

  • Miss Dx. Luv it!  [ Fri Nov 5 2010 6:56 PM ]

    Unlike the previous comment, I really enjoyed your article. How sad that the "keep my diagnosis a secret" individual did not take the time to read your article. Specifically:

    "This is not just about people drinking too many sodas and watching too much television. This disease is steeped in cultural and economic factors like poverty, education, family structure, employment opportunities and access to care. It’s easy to tell people to diet and exercise. It’s hard to create an environment in which people actually have the knowledge, motivation, and social and financial resources to make it happen."

    The spoon at the Flying Star is in my hands. So is my will to get up and go to the gym. Keep writing, and thanks for doing what you do.

    Closet DM, even if you keep it a secret...everyone already knows who you are. It's not a secret. What is a secret to everyone else is why you choose to blame others for your lifestyle.

  • @crankytype2  [ Fri Nov 5 2010 7:18 PM ]

    Hi Cranky,

    I understand why you take this article personally and interpret what I'm saying as a regurgitation of the stigma you so often suffer in association with your disease. But it's not intended, nor written, as an attack on people with diabetes. Remember this paragraph?

    "Not everyone who has the disease is overweight or sedentary. The last guy I took care of with type 2 diabetes was probably 125 pounds dripping wet. Certain minority groups are more likely to get the disease, even when matched for weight and age to their Caucasian counterparts. Minorities also tend to develop a more aggressive form of the disease. Add this to the fact that minorities are less likely to have access to insurance and health care, and you’ve got a recipe for disaster."

    Nor do I suggest that the solution to diabetes lies in "faulting" any "fat lazy pigs":

    "Clearly, diabetes is a public health issue that raises more questions than answers. This is not just about people drinking too many sodas and watching too much television. This disease is steeped in cultural and economic factors like poverty, education, family structure, employment opportunities and access to care. It’s easy to tell people to diet and exercise. It’s hard to create an environment in which people actually have the knowledge, motivation, and social and financial resources to make it happen."

    I know you feel that I, by restating the fact that diabetes is almost completely preventable, am reinforcing a stereotype. But I'm discussing a fact, not some opinion of mine. From the CDC's 2007 National Diabetes Fact Sheet:

    "Progression to diabetes among those with prediabetes is not inevitable. Studies have shown that people with prediabetes who lose weight and increase their physical activity can prevent or delay diabetes and return their blood glucose levels to normal.

    • The Diabetes Prevention Program, a large prevention study of people at high risk for diabetes, showed that lifestyle intervention reduced developing diabetes by 58% during a 3-year period. The reduction was even greater, 71%, among adults aged 60 years or older.

    • Interventions to prevent or delay type 2 diabetes in individuals with prediabetes can be feasible and cost-effective. Research has found that lifestyle interventions are more cost-effective than medications."

    This prevention is what I'm talking about when I say we must make the necessary changes, and nowhere do I say the burden of change rests on the shoulders of those with the disease. I argue it must be a society-wide effort.

    I know it's enraging to have a disease that people perceive as "your fault." It wasn't my intention to echo that sentiment here (nor do I think I do). But it's also not my intention to sugarcoat the strong associations between diabetes 2, weight, and lifestyle. Nor is there any point in sugarcoating the devastating consequences of diabetes. Many people without diabetes don't understand the fact that people can lose vision, or limbs, or kidneys, or quality of life, just from having high blood sugar. Would we let people lose vision, and kidneys, and limbs from Ebola, or would we organize quickly and efficiently to stop it? So why aren't we doing the same for diabetes? The strong language and comparison to diseases like Ebola clearly serves the purpose of illustrating how we, as a society, should think of diabetes and our response to it the same way we think of responding to more "attention-grabbing" diseases like Ebola. The point clearly isn't to say, as you suggest, "you're going to die a horrible death and it's all your fault." My suggestion throughout the article is society-wide prevention, not individual changes.

    "Diabetes won't abdicate its destructive throne on its own. We, as a society, must empower one another to make the necessary changes. So our first challenge, as we move into a future in which one in three Americans could develop diabetes, is to make this real to people."

    Anyhow, I apologize that this article rubbed you the wrong way. This wouldn't be my approach with a patient of mine. But this article wasn't written for patients. It was written for the 24 year old Alibi reader who usually skips to the music section and isn't thinking about tomorrow and doesn't give a damn about this disease. Like I said, my goal was to "make this real to people," not offer a management plan for victims of the disease.

    Thank you for your thoughts. I will consider them the next time I'm writing about a disease with a stigma or stereotype attached to it. It's always important to be reminded of how people who actually suffer from a particular condition perceive what's being tossed around in the media.

  • @crankytype2 also  [ Fri Nov 5 2010 7:43 PM ]

    The quote you cited is from a blog written by a dude who has a wife with Type 1 diabetes. If you think my article was offensive, here's a picture of him holding a bunch of fat!!!

    [link]!/photo.php?fbid=287382139962&set=a.204889069962.26650.5457479962

  • Crankytype2's cranky comments  [ Tue Nov 9 2010 1:56 PM ]

    Interesting comment from a cranky Diabetic....Bravo to Ms. Doyle for her excellent fact-based retort on this disease. Although there is a genetic component to the disease it DOES NOT completely dictate if one will have Diabetes. The problem is that lifestyles have made it much easier for Diabetes to manifest itself in a genetically susceptible person. If it were soley genetics, then why have the rates gone up and are expected to triple by 2050?? Why are children now having hypertension and DiabetesType 2 at younger ages?

  • Blame game or hopeful  [ Fri Nov 19 2010 12:35 PM ]

    Miss D,

    Enjoyed your article in highlighting the fact that diabetes type II is very much overlooked in the media. It's not a fancy or flashy disease as some of the infectious disease you mentioned. I applaud you for spotlighting this major health problem.

    I personally do not have diabetes, but have loved ones who do have it and instead of seeing your article as a blame game, I rather see it as hopeful. It is hopeful in the sense that unlike some diseases, those with impaired fasting glucose aka pre-diabetes, can actually stop it's progression into full-blown diabetes. I don't know about you, but that leaves me hopeful in that I can actually change the outcome. If one does indeed progress to full diabetes, then one still has hope in turning things around by changing lifestyles and eating right.

    I had a patient 2 days ago with diabetes type II. His sugar was in the high 200's and his HgA1C was in the 9's. He was steadily going the wrong direction as far as his labs go. In asking what happened, he shared his alcohol intake and his eating habits which included eating out often. I shared how worried I am for his kidneys since he already had proteinuria. I then asked how I can help him with moving in the right direction in his labs and protecting the overall health of his organs. He smiled and said, "I know what I need to do and I know it's all up to me to do it. I can do this." I saw the hope in his eyes and the determination to succeed. I am his resource.

    That's how I saw your article, as a fun resource with facts and truths throughout. I do not in any way feel that your article was meant for patients and even if a patient were to read it, the hope is in the details.

 
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